Myostatin is a well-characterized negative regulator of skeletal muscle and can inhibit myogenesis and stimulate adipogenesis. Clone Myo 2/1A has been shown to have the reverse effect, up-regulate myogenesis and down-regulate adipogenesis.
Clone 399R is used to detect plasma adiponectin concentrations for type-2 diabetes and obesity related causes.
Clone 32F8 is used to detect plasma adiponectin concentrations for type-2 diabetes and obesity related causes.
Clone 72B can be used in assays to detect GDF9 expression and help diagnose ovarian disorders.
Clone 53/1 can be used in assays to detect oocyte expression and has been shown to neutralize GDF9 biological activity.
Clone 28A has been used to detect BMP15 expression and biosynthesis in various carcinoma progression studies.
Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLPC1 is used in the detection of PLP by various analysis methods.
Clone PO 23/32 is useful in detecting inhibin α levels in cancer cells.
Clone PO 12/8 is useful in detecting inhibin α levels, especially in prostate cancer cells.
Clone 133 recognizes the α isoform of PKCα and binds to a sequence at the C terminus of PKCα to detect its expression in vitro.