Category Archive for ‘Endocrinology’

Myostatin is a well-characterized negative regulator of skeletal muscle and can inhibit myogenesis and stimulate adipogenesis. Clone Myo 2/1A has been shown to have the reverse effect, up-regulate myogenesis and down-regulate adipogenesis.

Clone 53/1 can be used in assays to detect oocyte expression and has been shown to neutralize GDF9 biological activity.

Clone 28A has been used to detect BMP15 expression and biosynthesis in various carcinoma progression studies.

Clone PO 23/32 is useful in detecting inhibin α levels in cancer cells.

Clone PO 12/8 is useful in detecting inhibin α levels, especially in prostate cancer cells.

Clone 3/11A recognizes DAZL at its C terminus, and is used in detection of DAZL expression by various methods.

MBP Clone 14 recognizes an epitope in the 36-50 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP.

β-C Clone 1 recognizes the β-C subunit of Activin and is a useful stain to detect expression of the protein in hepatocyte cells.

29/9 is a clone raised against recombinant Fst 288, and is used in combination, commonly as the capture, with antibody 17/2 in a two site ELISA for the detection of Follistatin.

Clone PPG5/25 recognizes Estrogen Receptor Beta (ERβ) 5 and is useful in determining the expression of ERβ5 in cancer cells, mainly via immunohistochemistry.