Myostatin is a well-characterized negative regulator of skeletal muscle and can inhibit myogenesis and stimulate adipogenesis. Clone Myo 2/1A has been shown to have the reverse effect, up-regulate myogenesis and down-regulate adipogenesis.
Clone 53/1 can be used in assays to detect oocyte expression and has been shown to neutralize GDF9 biological activity.
Clone 28A has been used to detect BMP15 expression and biosynthesis in various carcinoma progression studies.
Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLPC1 is used in the detection of PLP by various analysis methods.
Clone 133 recognizes the α isoform of PKCα and binds to a sequence at the C terminus of PKCα to detect its expression in vitro.
Clone 98/P12 is a useful detector of phosphorylated MBP by binding to Thr98 of human MBP in the phosphorylated state.
Clone 3/11A recognizes DAZL at its C terminus, and is used in detection of DAZL expression by various methods.
MBP Clone 14 recognizes an epitope in the 36-50 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP.
MBP Clone 12 recognizes an epitope in the 82-87 region of MBP, useful in clinical diagnosis to detect MBP levels or myelination in human MBP.
MBP Clone 1 recognizes an epitope in the 129-138 region of MBP, useful in clinical diagnosis to detect MBP levels.