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Next Generation Sequencing (NGS) for genetic disorders

Next Generation Sequencing (NGS) is a DNA sequencing technology which has revolutionised genomic research. Using NGS an entire human genome can be sequenced within a single day. CleanPlex NGS panels are powered by Paragon Genomics’ CleanPlex Technology, which uses a proprietary multiplex PCR background cleaning chemistry to effectively remove non-specific PCR products, resulting in best-in-class target enrichment performance and efficient use of sequencing reads. CleanPlex Ready-to-Use NGS Panels are expertly optimized to generate valuable insights.

 Mitochondrial Disease CleanPlex Panel

The CleanPlex Mitochondrial Disease Panel is a multiplex PCR-based targeted resequencing assay designed to simplify the evaluation of the entire human mitochondrial genome for mutations. The panel enriches for and provides complete coverage of all 37 genes of the ~17 kb mitochondrial genome, allowing identification of important variants.

CFTR CleanPlex Panel

The CleanPlex CFTR Panel is a multiplex PCR-based targeted resequencing assay designed to simplify the evaluation of germline variants across the CFTR gene.

 Hereditary Cancer CleanPlex Panel

The CleanPlex Hereditary Cancer Panel v2 is a targeted resequencing assay designed for analyzing genes associated with an increased risk of developing hereditary cancers. The panel is expertly curated using the latest research findings to target 37 genes and both single nucleotide variants (SNVs) and insertion-deletion mutations (indels).