Next Generation Sequencing for cancer research
Next Generation Sequencing (NGS) is a DNA sequencing technology which has revolutionised genomic research. Using NGS an entire human genome can be sequenced within a single day. CleanPlex NGS panels are powered by Paragon Genomics’ CleanPlex Technology, which uses a proprietary multiplex PCR background cleaning chemistry to effectively remove non-specific PCR products, resulting in best-in-class target enrichment performance and efficient use of sequencing reads.
Paragon Genomics developed CleanPlex Oncology Panels for assessing certain genes, gene regions or gene mutations in a sample of cancer tumor tissue or blood liquid biopsy in order to detect rare mutations and cancer subclones and identify potential driver mutations.
BRCA1 & BRCA2 Panel | The CleanPlex BRCA1 & BRCA2 Panel is a multiplex PCR- based targeted resequencing assay designed to simplify the evaluation of somatic and germline variants across BRCA1 and BRCA2 genes. |
UMI Lung Cancer Panel | The CleanPlex UMI Lung Cancer Panel is a targeted resequencing assay designed for rapid and high confident detection of ultralow frequency variants across the hotspot regions of 23 genes associated with lung cancer. |
Hereditary Cancer Panel | The CleanPlex Hereditary Cancer Panel is a targeted resequencing assay designed for analyzing genes associated with an increased risk of developing hereditary cancers. The panel is expertly curated using the latest research findings to target 37 genes and both single nucleotide variants (SNVs) and insertion-deletion mutations (indels). |
OncoZoom Cancer Panel | The CleanPlex OncoZoom Cancer Hotspot Panel is a multiplex PCR-based targeted resequencing assay designed for rapid detection of somatic mutations across the hotspot regions of 65 oncogenes and tumor suppressor genes. |
TP53 Panel | The CleanPlex TP53 Panel is a multiplex PCR-based targeted resequencing assay designed to simplify the evaluation of somatic and germline variants across the TP53 gene. |
| Product code | Product image | Product name | Platform | Pack size | Downloads | Price | Buy |
|---|---|---|---|---|---|---|---|
| 916066 |  | CleanPlex UMI Lung Cancer Panel (96) | Illumina, Ion torrent | 96 reactions | £17,160.00 | | |
| 916064 | | CleanPlex UMI Lung Cancer Panel | Illumina, Ion torrent | 8 reactions | £1,950.00 | | |
| 916115 | | CleanPlex Hereditary Cancer Panel (96) | Illumina, Ion torrent | 96 reactions | £17,160.00 | | |
| 916114 | | CleanPlex Hereditary Cancer Panel | Illumina, Ion torrent | 8 reactions | £1,950.00 | | |
| 916008 | | CleanPlex TP53 Panel | Illumina, Ion torrent | 8 reactions | £512.00 | | |
| 916009 | | CleanPlex TP53 Panel (96) | Illumina, Ion torrent | 96 reactions | £4,368.00 | | |
| 916113 | | CleanPlex BRCA1 & BRCA2 Panel (96) | Illumina, Ion torrent | 96 reactions | £7,072.00 | | |
| 916112 | | CleanPlex BRCA1 & BRCA2 Panel | Illumina, Ion torrent | 8 reactions | £824.00 | | |
| 916002 | | CleanPlex OncoZoom Cancer Hotspot Panel (96) | Illumina, Ion torrent | 96 reactions | £8,528.00 | | |
| 916001 | | CleanPlex OncoZoom Cancer Hotspot Panel | Illumina, Ion torrent | 8 reactions | £1,014.00 | |