Anti-Myelin Basic Protein Clone 98/P12

The phosphorylation of myelin basic protein (MBP) has been shown to decrease the ability of MBP to aggregate lipid vesicles and consequently destabilising the compact structure of myelin, a destruction that has been observed in demyelinating diseases such as Multiple Sclerosis. (Yon, M et al. 1995) Clone 98/P12 is a useful detector of phosphorylated MBP by binding to Thr98 of human MBP in the phosphorylated state.

Catalogue No. Target Research Areas Applications Size Price (£)
98/P12-100UG Myelin Basic Protein (Thr98) Immunology
Neuroscience
Cell biology
ELISA
WB
ICC
0.1mg 347.00

Clone 98/P12 used to detect MBP in brain tissue of normal and MS patients by Western Blot

Western Blot reacted with mAb P12. Lane 8, normal; lane 9, MS 75. (Yon, M et al. 1996)
Dilution used: 1:2000

Clone 98/P12 used to stain OL cells and detect MBP levels by ICC

Colocalization of various lipids and proteins in the developing oligodendrocyte… b: Mature oligodendrocytes fixed at 15 DIV. (DeBruin, L.S et al. 2005)
Dilution used: 1:400

ELISA using clone 98/P12 to test its immunoreactivity against synthetic peptides and proteins

(Yon, M et al. 1995)

Menu