Anti-Myostatin Clone Myo2/1A

Myostatin is a well-characterized negative regulator of skeletal muscle and can inhibit myogenesis and stimulate adipogenesis. Clone Myo 2/1A has been shown to have the reverse effect, up-regulate myogenesis and down-regulate adipogenesis. (Artaza, N et al.)

Catalogue No. Target Research Areas Applications Size Price (£)
Myo2/1A-100UG Myostatin Endocrinology WB
IHC
ICC
0.1mg 300.00

Clone Myo 2/1A used to detect Myostatin expression by ICC

Effect of recombinant Mst-113 protein and anti-Mst antibody on myogenesis in differentiating C3H 10T(1/2), assessed by using myogenin immunocytochemical staining. Cells were incubated with medium alone (C, control), graded concentrations of recombinant Mst-113 or anti-Mst antibody (Mst Ab) for 1 wk. A, Immunocytochemical staining using an antibody against myogenin; quantitative image analysis of stained cells is shown in B. Asterisks denote the P values for the statistical comparison of treatment group against medium control. No 1st Ab, Cells not treated with first antibody. Magnification, ×400 (Artaza, N et al.)
Dilution used: 100 μg/mL

Clone Myo 2/1A used to detect Myostatin expression by Western Blot with detection at 52 kDa

A: Luminol detection of Western blots with monoclonal antibody against Mst at 3 d after transfection (Artaza, N et al.)
Dilution used: 1:500

Clone Myo 2/1A used to detect C/EBP α to assess adipogenic differentiation C3H 10T(1/2) by IHC

Image caption: B, Cells were incubated for 4 d (C/EBPα) and 1 wk (adiponectin) with graded concentrations of recombinant Mst-113 or anti-Mst antibody, and plates were divided for either trypsination and Western blot on the cell extracts (30 μg/lane) with an antibody against C/EBP-α
(Artaza, N et al.)
Dilution used: 100 μg/mL

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