Description
The CleanPlex Mitochondrial Disease Panel is a multiplex PCR-based targeted resequencing assay designed to simplify the evaluation of the entire human mitochondrial genome for mutations. The panel enriches for and provides complete coverage of all 37 genes of the ~17 kb mitochondrial genome, allowing identification of important variants. Starting with just 2 ng of high-quality genomic DNA (1 ng per primer pool), sequencing-ready libraries can be prepared using a streamlined workflow in just 3 hours. The panel is optimized to deliver data with high on-target performance and high coverage uniformity to ensure efficient use of sequencing reads.
Highlights
- Relevant Gene Content
Detect and investigate important variants with complete coverage of the entire human mitochondrial genome - Fast, Streamlined Workflow
Generate sequencing-ready libraries in just 3 hours using a rapid, three-step protocol - Superb Performance
Prepare high-quality NGS libraries with excellent on-target performance using CleanPlex Technology to enable efficient use of sequencing reads and reduce costs
The CleanPlex Mitochondrial Disease Panel contains CleanPlex Multiplex PCR Primers and CleanPlex Targeted Library Kit. CleanPlex Indexed PCR Primers and CleanMag Magnetic Beads are ordered separately to complete the workflow from input DNA to sequencing-ready NGS libraries.