Anti-infection chemical
Praziquantel is an anthelmintic effective against flatworms.
Praziquantel 10mM (1mL in DMSO)
£129.00
Target: flatworms
Chemical name: 2-(cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one
Formula: C19H24N2O2
Molecular weight: 312.41
Purity: 99.6 % (HPLC)
Solubility: 63 mg/mL (DMSO), 63 mg/mL (ethanol)
Size: 10mM (1mL in DMSO)
Storage: 3 years -20°C powder, 2 years -80°C in solvent
Praziquantel is a highly effective broad-spectrum anthelmintic agent against many trematodes and cestodes. It is mainly used for the treatment of schistosomiasis (bilharziosis). No teratogenicity has been reported in animal studies. Over the last decades millions of pregnant women have been inadvertently treated with praziquatel during routine anthelmintic programs without an obvious adverse reactions reported. A few publications also found no evidence of a teratogenic potential after mothers had been treated in the first trimester (Adam 2004a, Paparone 1996). In a study from Uganda encompassing more than 1,000 pregnant women, treatment with praziquantel in the second and third trimester was not associated with an increase in adverse outcomes (Ndibazza 2010).