SARS-CoV-2 Spike Antigen B.1.525 (UK/Nigerian Variant)

All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. Spike protein of the mutant strain B.1.525 is a full-length protein, which is active in its native trimeric form, that is stabilized in LMNG detergent.

UK/Nigerian Variant Features

Product Name: SARS-CoV-2 full-length Trimeric Spike Recombinant Antigen (Brazil Variant)
PHE Reference: VUI-21FEB-03
UniProt Number: P0DTC2
Host: HEK293
Mutations that differ from SPIKE Protein: del 69-70, del 144, Q52R, E484K, Q667H, F888L
Further Modifications: Furin cleavage site “RRAR” mutated to “GSAG”; K986P; V987P
Buffer Composition: 20 mM Hepes pH 7.5; 150 mM NaCl, 0.001% LMNG
Molecular Weight: 3 x 142 kDa = 426 kDa