SARS-CoV-2 Spike Antigen P.1 (Brazil Variant)

All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. Spike protein of the mutant strain P.1, also commonly known as the “Brazil Variant”. It is a full-length protein, which is active in its native trimeric form, that is stabilized in LMNG detergent.

Brazil Variant Features

Product Name: SARS-CoV-2 full-length Trimeric Spike Recombinant Antigen (Brazil Variant)
WHO Label: Gamma
UniProt Number: P0DTC2
Host: HEK293
Mutations that differ from SPIKE Protein: L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, H655Y, T1027I, V1176F
Further Modifications: Furin cleavage site “RRAR” mutated to “GSAG”; K986P V987P
Buffer Composition: 20 mM Hepes pH 7.5; 150 mM NaCl, 0.001% LMNG
Molecular Weight: 142 kDa