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SARS-CoV-2 full-length Trimeric Spike Recombinant Antigen B.1.429 Mutation (California Variant) (100 μg)

£610.00

100 μg

SKU: BSV-COV-PR-82

All viruses undergo fast mutations and adept quickly to the countermeasures that the immune systems creates against them. SARS-CoV-2 of the COVID-19 pandemic is no exception here. During the pandemic multiple mutant strains arose. Spike protein of the mutant strain B.1.429 is a full-length protein, which is active in its native trimeric form, that is stabilized in LMNG detergent.

B.1.429_Datasheet

Features

Product Name: SARS-CoV-2 full-length Trimeric Spike Recombinant Antigen B.1.429 Variant
CDPH Reference: CAL.20C
UniProt Number: P0DTC2
SARS-CoV-2 Protein: B.1.429 Mutation
Host: HEK293
Tag: C-terminal Rho1D4
Mutations that differ from SPIKE Protein: S13l; W152C; L452R; D1183Y
Further Modifications: 

  • Furin cleavage site “RRAR” mutated to “GSAG”; K986P; V987P
  • C-terminal Rho1D4 tag fused with spacer “GSSG” to protein sequence

Buffer Composition: 20 mM Hepes pH 7.5; 150 mM NaCl, 0.001% LMNG
Molecular Weight: 1286 amino acids (including Rho1D4 tag and linker), 142.115 kDa

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